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LAVA Therapeutics, Merck Partner on KEYTRUDA Combo

Merck will provide pembrolizumab for the dose escalation and expansion phases of LAVA’s Phase 1/2a study in mCRPC.

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By: Kristin Brooks

Managing Editor, Contract Pharma

LAVA Therapeutics N.V. has entered into a clinical trial collaboration and supply agreement with Merck to evaluate its anti-PD-1 therapy KEYTRUDA (pembrolizumab) in combination with LAVA-1207, a Gammabody designed to target the prostate-specific membrane antigen (PSMA) to trigger the potent and preferential killing of PSMA-positive tumor cells, in metastatic castration-resistant prostate cancer (mCRPC).   Merck will provide pembrolizumab for the dose escalation and expansion phases of LAVA’s o...

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